Thomas J Rosol Selected Research

Parathyroid Hormone-Related Protein

1/2021	In Vivo Tumorigenesis, Osteolytic Sarcomas, and Tumorigenic Cell Lines from Transgenic Mice Expressing the Human T-Lymphotropic Virus Type 1 (HTLV-1) Tax Viral Oncogene.
1/2020	Parathyroid hormone-related protein promotes bone loss in T-cell leukemia as well as in solid tumors.
9/2017	HTLV-1 viral oncogene HBZ induces osteolytic bone disease in transgenic mice.
4/2017	Animal Models of Cancer-Associated Hypercalcemia.
1/2015	TGF-β Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepatocellular Carcinoma.
6/2012	Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma.
5/2012	Evaluating the effects of mixed osteolytic/osteoblastic metastasis on vertebral bone quality in a new rat model.
4/2012	Effects of parathyroid hormone-related protein and macrophage inflammatory protein-1α in Jurkat T-cells on tumor formation in vivo and expression of apoptosis regulatory genes in vitro.
5/2011	The calcium-sensing receptor is necessary for the rapid development of hypercalcemia in human lung squamous cell carcinoma.
6/2010	The midregion, nuclear localization sequence, and C terminus of PTHrP regulate skeletal development, hematopoiesis, and survival in mice.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Thomas J Rosol Research Topics

Disease

61	Neoplasms (Cancer) 10/2021 - 01/2002
21	Neoplasm Metastasis (Metastasis) 10/2021 - 02/2003
16	Prostatic Neoplasms (Prostate Cancer) 08/2021 - 11/2003
9	Hypercalcemia (Milk Alkali Syndrome) 01/2020 - 07/2002
9	Breast Neoplasms (Breast Cancer) 01/2018 - 05/2005
7	Bone Resorption 01/2021 - 07/2008
6	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 10/2021 - 12/2007
6	Humoral Hypercalcemia Of Malignancy 04/2017 - 01/2002
6	Carcinoma (Carcinomatosis) 07/2015 - 01/2002
5	Hyperplasia 12/2020 - 02/2013
5	Carcinogenesis 01/2015 - 05/2005
4	Osteolysis 10/2021 - 07/2008
4	Bone Neoplasms (Bone Cancer) 01/2020 - 10/2005
3	Squamous Cell Carcinoma of Head and Neck 08/2018 - 11/2010
3	Type 2 Diabetes Mellitus (MODY) 10/2015 - 02/2013
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2015 - 02/2002
3	Hypocalcemia 01/2015 - 02/2003
3	Pain (Aches) 04/2011 - 10/2005
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 11/2006 - 04/2005
2	Inflammation (Inflammations) 01/2021 - 02/2010
2	Hypertrophy 12/2020 - 07/2015
2	Necrosis 02/2016 - 11/2012
2	Hyperphosphatemia 01/2015 - 05/2007
2	Infections 01/2015 - 06/2008
2	Noninfiltrating Intraductal Carcinoma (DCIS) 04/2013 - 02/2013
2	Osteoporosis 01/2012 - 01/2009
2	Lung Neoplasms (Lung Cancer) 05/2011 - 01/2007
2	Disease Progression 11/2008 - 09/2006
2	Hypokalemia 05/2007 - 03/2005
2	Paraneoplastic Syndromes (Paraneoplastic Syndrome) 01/2005 - 02/2002
1	Arthritis (Polyarthritis) 01/2021
1	T-Cell Leukemia (Leukemia, T Cell) 01/2020
1	T-Cell Lymphoma (Lymphoma, T Cell) 12/2019
1	Genomic Instability 01/2018
1	Multiple Myeloma 05/2017
1	Liver Neoplasms (Liver Cancer) 05/2017
1	Triple Negative Breast Neoplasms 01/2017

Drug/Important Bio-Agent (IBA)

21	Parathyroid Hormone-Related ProteinIBA 01/2021 - 01/2002
8	CalciumIBA 01/2021 - 05/2007
8	Proteins (Proteins, Gene)FDA Link 08/2016 - 07/2002
7	Pharmaceutical PreparationsIBA 12/2020 - 02/2003
6	Zoledronic Acid (Zometa)FDA Link 10/2021 - 12/2007
6	LuciferasesIBA 01/2020 - 02/2003
6	Messenger RNA (mRNA)IBA 01/2016 - 02/2002
4	Parathyroid Hormone (Parathormone)IBA 01/2015 - 02/2003
3	Biological ProductsIBA 12/2019 - 11/2003
3	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018 - 03/2010
3	TensinsIBA 01/2018 - 03/2010
3	Transcription Factors (Transcription Factor)IBA 03/2017 - 02/2010
3	Estrogen ReceptorsIBA 01/2017 - 04/2013
3	Glucagon-Like Peptide 1 (GLP 1)IBA 10/2015 - 02/2013
3	Diphosphonates (Bisphosphonates)IBA 06/2011 - 11/2010
2	Histone Deacetylase InhibitorsIBA 10/2021 - 05/2017
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 11/2008
2	Capsules (Microcapsules)IBA 07/2018 - 11/2012
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 07/2018 - 11/2012
2	ChromatinIBA 05/2017 - 01/2016
2	human ERBB2 proteinIBA 01/2017 - 05/2005
2	Progesterone Receptors (Progesterone Receptor)IBA 01/2017 - 05/2005
2	Hematoxylin (Haematoxylon)IBA 02/2016 - 02/2013
2	Eosine Yellowish-(YS) (Eosin)IBA 02/2016 - 02/2013
2	BombesinIBA 01/2016 - 01/2016
2	Peptides (Polypeptides)IBA 01/2016 - 01/2005
2	Complementary DNA (cDNA)IBA 01/2016 - 11/2008
2	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 07/2015 - 02/2013
2	Biomarkers (Surrogate Marker)IBA 05/2014 - 11/2006
2	CollagenIBA 01/2014 - 06/2011
2	Corn Oil (Oil, Corn)IBA 02/2013 - 05/2005
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 02/2013 - 09/2007
2	Fish OilsIBA 02/2013 - 05/2005
2	Calcium-Sensing ReceptorsIBA 06/2011 - 05/2011
2	Tartrate-Resistant Acid PhosphataseIBA 11/2010 - 08/2004
2	Conditioned Culture MediaIBA 04/2010 - 03/2004
2	Estrogens (Estrogen)FDA Link 01/2009 - 05/2005
2	Insulin (Novolin)FDA Link 05/2007 - 03/2005
2	ElectrolytesIBA 05/2007 - 03/2005
2	Analgesics (Analgesic Drugs)IBA 09/2006 - 10/2005
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 03/2004 - 02/2002
1	CarcinogensIBA 08/2021
1	ethyl acrylateIBA 08/2021
1	pyrazolanthroneIBA 08/2021
1	Drinking WaterIBA 08/2021
1	Granzymes (Granzyme)IBA 01/2021
1	LipopolysaccharidesIBA 01/2021
1	InterferonsIBA 01/2021
1	Food Additives (Food Additive)IBA 12/2020
1	Oncogene Proteins (Oncogene Protein)IBA 12/2019
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 10/2018
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 08/2018
1	Growth Factor ReceptorsIBA 07/2018
1	ErbB Receptors (EGF Receptor)IBA 01/2018
1	Basic-Leucine Zipper Transcription FactorsIBA 09/2017
1	CytokinesIBA 04/2017
1	Taxoids (Taxanes)IBA 01/2017
1	AnthracyclinesIBA 01/2017
1	Oxidoreductases (Dehydrogenase)IBA 01/2017

Therapy/Procedure

19	Therapeutics 10/2021 - 02/2003
5	Injections 01/2020 - 08/2006
3	Castration 11/2016 - 12/2013
1	Mammaplasty (Breast Reconstruction) 01/2018